The point of abstraction is that you can use it without understanding what's behind it, not that you should. There are diminishing returns after couple of levels, but abstractions in general don't come from thin air, and it's a massively easier to use an abstraction if you have some understanding of a level or two below it. It gets even more important when an abstraction is buggy, leaky, incomplete, or imprecise.

So yeah, quantum mechanics may not help you much when writing JavaScript, but understanding of lower-level programming, of how memory and networks work, just might.