We used c3. But switched to Vega-lite. It is another wrapper on D3 but it’s well thought out and the defaults are really good. It has university backing. We vega lite for our web based software (it reminds me of R’s ggplot2)

https://vega.github.io/vega-lite/

They have a python graphing lib too based on the same “grammar of graphics”

https://altair-viz.github.io/