The results and conclusions here are rather interesting:
> Results
> After adjustment for covariates, the habitual use of vitamin D supplements was significantly associated with a 34% lower risk of COVID-19 infection (OR, 0.66; 95% CI, 0.45–0.97; P = 0.034). Circulating vitamin D levels at baseline or genetically predicted vitamin D levels were not associated with the risk of COVID-19 infection. The association between the use of vitamin D supplements and the risk of COVID-19 infection did not vary according to the different levels of circulating or genetically predicted vitamin D (P-interactions = 0.75 and 0.74, respectively).
> Conclusions
> Our findings suggest that habitual use of vitamin D supplements is related to a lower risk of COVID-19 infection, although we cannot rule out the possibility that the inverse association is due to residual confounding or selection bias. Further clinical trials are needed to verify these results.
I'm a little puzzled why taking vitamin D supplements was associated with lower risk of COVID infection, but vitamin D levels were not. This suggests that vitamin D might not do anything as a post-infection intervention.
It's also important to note that this was a prospective study, meaning people were enrolled before they became sick. So, they're not just using data from sick people to correlate vitamin D levels with outcomes like many other studies have done.
Taking any supplement, isn’t about the supplement but more about the ratio. For Vitamin D to be effective, it needs to correlate with Vitamin A in the beta-carotene format. When you get this balance right, you improve your ability to fight off infections.
To understand all your ratios, get tested with a Hair Tissue Mineral Analysis. Know your #s!!
> Results
> After adjustment for covariates, the habitual use of vitamin D supplements was significantly associated with a 34% lower risk of COVID-19 infection (OR, 0.66; 95% CI, 0.45–0.97; P = 0.034). Circulating vitamin D levels at baseline or genetically predicted vitamin D levels were not associated with the risk of COVID-19 infection. The association between the use of vitamin D supplements and the risk of COVID-19 infection did not vary according to the different levels of circulating or genetically predicted vitamin D (P-interactions = 0.75 and 0.74, respectively).
> Conclusions
> Our findings suggest that habitual use of vitamin D supplements is related to a lower risk of COVID-19 infection, although we cannot rule out the possibility that the inverse association is due to residual confounding or selection bias. Further clinical trials are needed to verify these results.
I'm a little puzzled why taking vitamin D supplements was associated with lower risk of COVID infection, but vitamin D levels were not. This suggests that vitamin D might not do anything as a post-infection intervention.
It's also important to note that this was a prospective study, meaning people were enrolled before they became sick. So, they're not just using data from sick people to correlate vitamin D levels with outcomes like many other studies have done.