I literally gave up on having a mailbox because of physical mail spam. I realized that they don't deliver mass mail to business addresses, and so I took down my mailbox and now just have all my mail sent to my work address. I've been doing it for ten years now, and it works, but it does lead to weirdness occasionally.
Most often I encounter people who actually get angry at me for not having a mailbox, call me selfish, call me the unibomber, tell me it is illegal. I still cannot figure out why people get emotionally charged about it.
A short while after I did it, the USPS reported to HUD that my address was vacant, and HUD reported that to the bank that holds my mortgage. This of course freaked them out until I explained to them what was going on.
I was also unable to take advantage of the free Covid test kits that the Federal government said were available to "every family in America". Turns out it was really every family in America with a residential mailbox. Ok, that was my choice, but there *are* still rural communities that rely on general delivery at the post office rather than individual mailboxes.
I do occasionally hit companies who's web app will tell me my address isn't good because it is a business address instead of a residential address. They are few enough though that I can just not do business with them and it hasn't impacted me much.