The exciting thing about these findings is not that the monkey's live longer, it... | Hacker News

Hacker Newsnew | past | comments | ask | show | jobs | submit

non- on Sept 12, 2024 | parent | context | favorite | on: Metformin decelerates aging clock in male monkeys

The exciting thing about these findings is not that the monkey's live longer, it's that their brains aged slower.

---

Highlights:

• Metformin prevents brain atrophy, elevating cognitive function in aged male primates

• Metformin slows the pace of aging across diverse male primate tissues

• Metformin counterparts neuronal aging, delivering geroprotection via Nrf2 in male primates

iwontberude on Sept 12, 2024 [–]

• Metformin-associated lactic acidosis has an estimated death rate of up to 50%.

giardini on Sept 13, 2024 | [–]

So... don't overdose?

iwontberude on Sept 15, 2024 | | [–]

It can build up over time and requires regular blood work.

Consider applying for YC's Fall 2026 batch! Applications are open till July 27.
Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact