To reduce the number of filters in Adblock, a simple way is to let it run for a few days with a popular black list such as EasyList. Then open the list in the preferences, sort it by number of hits, and unselect all the filters with 0 hits (there are so many of them, that probably something like 99% of them never get any hits). You can select the filters, and press "Space" to disable them all in one go.