I definitely get where this is coming from - I've been using gulp+browserify+watchify+react+express+mongoose lately, and even though I really do like all of the tools individually just wiring all of the different bits and pieces together feels like a chore and is very error-prone.

I think there's a lot of space in the frontend arena for a convention-over-configuration frontend framework that ties in ES6 & jsx transforms, jshint, css bundling, sourcemap generation, and production bundling & minification in a nice way with sane defaults and strong conventions.

That way I don't end up using http://octo-labs.github.io/snowflake/ for every JS project.